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Takayasu Arteritis discussion


This MRI angiography (gadolinium-enhanced / 1 breath hold - 34 sec ) image is from a 32 yo female patient with absent pulse in the right arm and transient ischemic attacks

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Congratulations to:

Marcelo Sá de Araujo - Rio de Janeiro - RJ
Lucas Neto - UFPE - Recife - PE - Brazil
Flávio Sallem - Brazil - São Luís - MA
Nilson Araujo-Brazil-RJ
Leandro K.B / Nelson Forjaz - UNIMAR - Marilia -SP
Evaldo Teixeira Nunes-Brasil-Piauí
Anber Ancel Tanaka-Brazil-Curitiba
Hugo Ballesteros-México-Distrito Federal
Amithai
Oscar Sveins Rincon Peña -Colombia-Boyacá
André Luiz de Albuquerque Pereira-Brazil-Rio de Janeiro
Marcos Arêas Marques - UFRJ - HUCFF
Fernanda Chagas Monteiro de Melo - Brasil -Rio -UFRJ
Eduardo Gaio - Brazil - DF
Sergio Augusto Rodrigues, Campo Grande MS Brazil
Santiago Araujo - Brazil - Piauí
Marcelo Sampaio Duran - Brazil - Rio de Janeiro
Fabio Moreira Andrade UFRJ
Eduardo F. Zanandrea -- UFES -- Vitoria
Antonio Bernardes - Sta. Casa - Rio - RJ
Joe Vialogo

Discussion

This patient physical examination revealed more signs:

  • Bruit over left subclavian artery
  • Her blood pressure was 130X90mmHg in the left arm and was inaudible in the rigth arm

    For purposes of classification, a patient shall be said to have Takayasu Arteritis if at least 3 of the following 6 criteria are present:

    Criterion Definition
    1. Age at disease onset =< 40 yr Development of symptoms or findings related to Takayasu arteritis at age =< 40 yr
    2. Claudication of extremities Development and worsening of fatigue and discomfort in muscles of >= 1 extremity while in use, especially the upper extremities
    3. Decreased brachial artery pulse Decreased pulsation of 1 or both brachial arteries
    4. BP difference > 10 mm Hg Difference of > 10 mm Hg in systolic BP between arms
    5. Bruit over subclavian arteries or aorta Bruit audible on auscultation over 1 or both subclavian arteries or abdominal aorta
    6. Arteriogram abnormality Arteriographic narrowing or occlusion of the entire aorta, its primary branches, or large arteries in the proximal upper or lower extremities, not due to arteriosclerosis, fibromuscular dysplasia, or similar causes; changes usually focal or segmental

    BP = blood pressure

    Arend WP et al. Arthritis Rheum. 1990;33:1129-1134.


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